Heterogeneity of DSM-IV Major Depressive Disorder as a Consequence of Subthreshold Bipolarity
Archives of General Psychiatry2009Vol. 66(12), pp. 1341–1341
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Petra Zimmermann, Tanja Brückl, Agnes Nocon, Hildegard Pfister, Roselind Lieb, Hans‐Ulrich Wïttchen, Florian Holsboer, Jules Angst
Abstract
Data suggest that MDD is a heterogeneous concept including a large group with subthreshold BPD, which is clinically significant and shares similarities with BPD. Findings might support the need for a broader concept and a more comprehensive screening of bipolarity, which could be substantial for future research and adequate treatment of patients with bipolarity.