Functional and Biochemical Alterations of the Medial Frontal Cortex in Obsessive-Compulsive Disorder
Archives of General Psychiatry2007Vol. 64(8), pp. 946–946
Citations Over TimeTop 1% of 2007 papers
Murat Yücel, Ben J. Harrison, Stephen J. Wood, Alex Fornito, R. Mark Wellard, Jesús Pujol, Kerrie Clarke, Mary L. Phillips, Michael Kyrios, Dennis Velakoulis, Christos Pantelis
Abstract
Hyperactivation of the MFC during high- vs low-conflict conditions in patients with OCD may be a compensatory response to a neuronal abnormality in the region. This relationship may partly explain the nature of inhibitory control deficits that are frequently seen in this group and may serve as a focus of future treatment studies.
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