Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis
JAMA2016Vol. 316(12), pp. 1279–1279
Citations Over TimeTop 1% of 2016 papers
Jeffrey L. Saver, Mayank Goyal, Aad van der Lugt, Bijoy K. Menon, Charles B.L.M. Majoie, Diederik W.J. Dippel, Bruce Campbell, Raul G. Nogueira, Andrew M. Demchuk, Alejandro Tomasello, Pere Cardona, Thomas Devlin, Donald Frei, Richard du Mesnil de Rochemont, Olvert A. Berkhemer, Tudor G. Jovin, Adnan Siddiqui, Wim H. van Zwam, Stephen M. Davis, Carlos Castaño, Biggya L. Sapkota, Puck Fransen, Carlos A. Molina, Robert J. van Oostenbrugge, Ángel Chamorro, Hester F. Lingsma, Frank L. Silver, Geoffrey A. Donnan, Ashfaq Shuaib, Scott Brown, Bruce C. Stouch, Peter Mitchell, Antoni Dávalos, Yvo B.W.E.M. Roos, Michael D. Hill, for the HERMES Collaborators
Abstract
In this individual patient data meta-analysis of patients with large-vessel ischemic stroke, earlier treatment with endovascular thrombectomy + medical therapy compared with medical therapy alone was associated with lower degrees of disability at 3 months. Benefit became nonsignificant after 7.3 hours.
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