An image‐based model of brain volume biomarker changes in Huntington's disease
Annals of Clinical and Translational Neurology2018Vol. 5(5), pp. 570–582
Citations Over TimeTop 10% of 2018 papers
P. A. Wijeratne, Alexandra L. Young, Neil P. Oxtoby, Razvan Marinescu, Nicholas C. Firth, Eileanoir B. Johnson, Amrita Mohan, Cristina Sampaio, Rachael I. Scahill, Sarah J. Tabrizi, Daniel C. Alexander
Abstract
We used a data-driven method to provide new insight into Huntington's disease progression as well as new power to stage and predict conversion. Our results highlight the potential of disease progression models, such as the event-based model, to provide new insight into Huntington's disease progression and to support fine-grained patient stratification for future precision medicine in Huntington's disease.
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