1(3)‐Formyl‐β‐carbolines: Potential Aldo‐X Precursors for the Synthesis of β‐Carboline‐Based Molecular Architectures
Citations Over TimeTop 14% of 2017 papers
Abstract
Abstract β‐Carboline, a privileged scaffold in the alkaloid family, has a broad spectrum of medicinal properties and is found in several commercial drugs, such as tadalafil, cipargamin, and abecarnil. Owing to the immense pharmacological importance of β‐carboline derivatives, their synthesis has been one of the frontier areas of research in recent years. In this context, 1(3)‐formyl‐9 H ‐β‐carbolines are promising “aldo‐X” bifunctional building blocks (AXB3s) that offer alternate avenues for the diversity‐oriented synthesis of β‐carboline derivatives. This Focus Review is an assimilation of recent literature (2011–2017) pertaining to the synthesis and applications of 1(3)‐formyl‐β‐carbolines for the construction of β‐carboline‐tethered and ‐fused molecular architectures. In addition, the medicinal potential of β‐carboline derivatives has been highlighted.
Related Papers
- Susquehanna Chorale Spring Concert "Roots and Wings"(2017)
- → DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION(2018)
- Коммуникaтивно- прaгмaтический aнaлиз дипломaтических бумaг (нa основе вербaльных нот)(2018)
- → ФОРМИРОВAНИЕ ГОТОВНОСТИ БУДУЩИХ ПЕДAГОГОВ К ОРГAНИЗAЦИИ РAБОТЫ ПО РAЗВИТИЮ ВAЛЕОЛОГИЧЕСКОЙ КУЛЬТУРЫ ШКОЛЬНИКОВ(2023)