Donepezil treatment is associated with improved outcomes in critically ill dementia patients via a reduction in delirium
Alzheimer s & Dementia2022Vol. 19(5), pp. 1742–1751
Citations Over TimeTop 10% of 2022 papers
Abstract
No pharmacologic treatments exist to reduce delirium in patients with dementia. Donepezil improves outcomes during critical illness in patients with dementia. Improved outcomes are mediated by a reduction in hospital delirium. Future studies in patients with dementia should prospectively evaluate donepezil in the prevention of delirium.
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