Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: Further support that PTPN22 is an autoimmunity gene
Arthritis & Rheumatism2005Vol. 52(6), pp. 1694–1699
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Anne Hinks, Anne Barton, Sally John, Ian N Bruce, Clive Hawkins, C.E.M. Griffiths, Rachelle Donn, Wendy Thomson, Alan J. Silman, Jane Worthington
Abstract
We replicated the findings of a previous association with RA and identified a novel association with JIA. Together with previous data showing associations with other autoimmune diseases, our findings provide further evidence that the PTPN22 gene plays a role in the pathogenesis of a subgroup of autoimmune diseases.
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