Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice
Arthritis & Rheumatism2011Vol. 63(3), pp. 738–748
Citations Over TimeTop 10% of 2011 papers
Yoshifumi Tada, Seiji Kondo, Shigehisa Aoki, Syuichi Koarada, Hisako Inoue, Rie Suematsu, Akihide Ohta, Tak W. Mak, Kohei Nagasawa
Abstract
Our results show that IRF5 is a crucial driver of lupus development in mice, and indicate that IRF5 may be an attractive new target for therapeutic intervention to control disease in SLE patients.
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