Network analysis of associations between serum interferon‐α activity, autoantibodies, and clinical features in systemic lupus erythematosus
Arthritis & Rheumatism2010Vol. 63(4), pp. 1044–1053
Citations Over TimeTop 10% of 2010 papers
Corinna E. Weckerle, Beverly S. Franek, Jennifer A. Kelly, Marissa Kumabe, Rachel A. Mikolaitis, Stephanie L. Green, Tammy O. Utset, Meenakshi Jolly, Judith A. James, John B. Harley, Timothy B. Niewold
Abstract
Our findings indicate that serum IFNα activity is strongly and consistently associated with autoantibodies, and not independently associated with clinical features in SLE. IFNα may be more relevant to humoral tolerance and initial pathogenesis than later clinical disease manifestations.
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