IgG4‐Related Disease: Clinical and Laboratory Features in One Hundred Twenty‐Five Patients
Arthritis & Rheumatology2015Vol. 67(9), pp. 2466–2475
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Zachary S. Wallace, Vikram Deshpande, Hamid Mattoo, Vinay S. Mahajan, Maria Kulikova, Shiv Pillai, John H. Stone
Abstract
Nearly 50% of this patient cohort with biopsy-proven, clinically active IgG4-RD had normal serum IgG4 concentrations. Elevations in the serum IgG4 concentration appeared to identify a subset of patients with a more severe disease phenotype. In addition, the levels of IgG4+ plasmablasts correlated well with the extent of disease activity.
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