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Toxicological Assessment of a Standardized Dry Extract of Zea mays L. (Poaceae) Stigmas During Gestation: Effects on Maternal Parameters and Fetal Outcomes in Wistar Rats
Birth Defects Research2025Vol. 117(9), pp. e2526–e2526
Graziele Alícia Batista Caixeta, Diego dos Santos Reis, Kássya Inácio Soares, I Ramos, Giovana Dantas Mendes, Pabline Silva Gasparoti, Monatha Nayara Guimarães Teófilo, Jamira Dias Rocha, Luiz Fernando Fróes Fleury, Elisa Flávia Luiz Cardoso Bailão, Clayson Moura Gomes, Wilson de Melo Cruvinel, Joelma Abadia Marciano de Paula, Vanessa Cristiane Santana Amaral
Abstract
Under these experimental conditions, the extract did not induce maternal or fetal toxicity. Nevertheless, the 1200 mg/kg dose may interfere with early pregnancy in Wistar rats.