Identification of microdeletions in candidate genes for cleft lip and/or palate
Birth Defects Research Part A Clinical and Molecular Teratology2009Vol. 85(1), pp. 42–51
Citations Over TimeTop 10% of 2009 papers
Min Shi, Adrianna Mostowska, Astanand Jugessur, Marla Johnson, M. Adela Mansilla, Kaare Christensen, Rolv T. Lie, Allen J. Wilcox, Jeffrey C. Murray
Abstract
These deletions suggest the potential roles of genes or regulatory elements contained within deleted regions in the etiology of clefting. Our analysis took advantage of genotypes from a candidate-gene-based SNP survey and proved to be an efficient analytical approach to interrogate genes potentially involved in clefting. This can serve as a model to find genes playing a role in complex traits in general.
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