The surgical significance of residual mucosal abnormalities in rectal cancer following neoadjuvant chemoradiotherapy
British journal of surgery2012Vol. 99(7), pp. 993–1001
Citations Over TimeTop 10% of 2012 papers
Abstract
In this series, the majority of patients with a complete pathological response did not have a complete clinical response. In tumours downstaged to ypT0/1 after CRT, residual mucosal abnormalities were predominantly small and had a 2 per cent risk of positive nodes, thus potentially facilitating transanal excision. The presence of adverse histological characteristics risk stratified tumours for nodal metastases.
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