Development of porous silicon‐coated gold nanoparticles as potential theragnostic material
Citations Over Time
Abstract
Abstract Gold nanoparticles (AuNPs) have been used widely as multifunctional materials for several biomedical applications due to their attractive characteristics. However, toxicity and aggregation of AuNPs are critical issues, and methods of effective surface modification are required to overcome these problems. In this study, porous silicon‐coated gold nanoparticles (AuNP@pSi) were fabricated as a hybrid nanocomposite capable of surface‐enhanced Raman scattering (SERS)‐sensing and drug carrier. First, size‐controlled AuNPs were coated with a silica nano‐shell, and the resulting silica layers were converted to porous silicon through magnesiothermic reduction. Overall results suggest that AuNP@pSi can be exploited as a SERS probe with efficient Raman signal improvement of benzenethiol as well as a drug carrier based on its high surface area (113.7 m 2 g −1 ) and porosity (13.38 nm, 0.3805 cm 3 g −1 ). Since the porous silicon possibly can serve as magnetic resonance imaging probes with DNP technology, this hybrid platform potentially can be utilized as powerful material capable of theragnosis system.
Related Papers
- → Design of C-dots/Fe3O4 magnetic nanocomposite as an efficient new nanozyme and its application for determination of H2O2 in nanomolar level(2017)67 cited
- → The effect of aqueous solution in Raman spectroscopy(2009)3 cited
- Structure and property of Cu-based thermosensitive nanocomposite(2006)
- → Bulk Metal and Ceramics Nanocomposites(2003)42 cited
- → Nanocomposites for Tissue Engineering(2010)11 cited