Is Alzheimer's disease an infectious neurological disease? A review of the literature
Brain and Behavior2022Vol. 12(8), pp. e2728–e2728
Citations Over TimeTop 10% of 2022 papers
Olivier Uwishema, Ashraf Mahmoud, Jeffrey Sun, Inês F. Silva Correia, Niovi Bejjani, Maria Alwan, Nicholas Aderinto, Adekunbi Oluyemisi, Burhan Dost
Abstract
While many studies reinforce the suspicion of an infectious etiology of AD, it is important to note that it is yet not validated how microorganisms' presence in the brain can develop AD due to the limited available evidence. Certainly, ground-breaking work is mandatory in this field of research, and these reports so far warrant a thorough investigation into how a chronic infection may remain silent while progressing its neuroinflammation. Amid this uncertainty arises the hope that many researchers will take on this challenge and join this endeavor to benefit AD patients worldwide.
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