A Novel MPT ‐Driven Necrosis‐Related lncRNA Signature for Prognostic Prediction in Hepatocellular Carcinoma: Validation Using Organoids
Cancer Medicine2025Vol. 15(1), pp. e71445–e71445
Yu Liu, Liye Tao, Zefeng Shen, Zheng Jiao, Yanru Wang, Meijie Chen, Yu Xie, Hongjun Chen, Jingwei Cai, Haoyu Pan, Shihao Li, Renan Jin, Junjie Xu, Xiao Liang
Abstract
The effective construction of an MPT-driven necrosis-related prognostic model highlights its potential to independently predict the prognosis of patients with HCC. These findings not only deepen our understanding of MPT-driven necrosis but also offer novel theoretical foundations for developing more effective treatment strategies. The gene LINC02313 has been identified as a promoter of HCC's ability to proliferate and invade, underscoring its potential as a therapeutic target for HCC.