Tumor Genomic and Transcriptomic Analysis Integrated With Liquid Biopsy ctDNA Monitoring: Analytical Validation and Clinical Insights
Cancer Medicine2025Vol. 14(23), pp. e71465–e71465
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Nam H. Tran, Thien‐Phuc Hoang Nguyen, Vinh Bui, Vu Le-Thuong, Trọng Khoa, Van‐Anh Nguyen Hoang, Tien Anh Nguyen, Minh‐Duc Nguyen, Hanh Thi Pham, Thuy Thi Bich Vo, My T. T. Ngo, Du Quyen Nguyen, Duy Sinh Nguyen, Hoai‐Nghia Nguyen, Minh‐Duy Phan, Hoa Giang, Lan N. Tu
Abstract
Comprehensive genomic and transcriptomic profiling could reliably unveil genetic details not provided by DNA-only CGP. The integration of ctDNA detection further helped detect tumor-agnostic mutations and monitor treatment response.