Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications
Citations Over TimeTop 10% of 2017 papers
Abstract
Abstract The use of deep eutectic solvent (DES)/water mixtures were explored for the selective enzymatic synthesis of α‐monobenzoate glycerol (α‐MBG) from glycerol and benzoic acid as substrates. Experiments were performed with four DES, three of them containing choline chloride (ChCl), combined with urea (URA), glycerol (GLY), and ethylene glycol (ETA) (in all cases ChCl/HBD 1:2 mol ratio), and another one formed with methylammonium chloride and glycerol (MA/GLY 1:3 mol ratio). The best conversions (99 %) were achieved with immobilized lipase B from Candida antarctica (CAL‐B) when ChCl/GLY was used as the solvent and the substrate at the same time. The use of water as a cosolvent (8 % v / v ) led to a significant decrease in the viscosity of the DES, and full conversions were then reached. Reusability studies of the biocatalyst revealed a 37 % decrease in activity after the first batch, but the activity remained mostly constant for the rest of the cycles.
Related Papers
- → Deep eutectic solvent system based on choline chloride-urea as a pre-treatment for nanofibrillation of wood cellulose(2015)282 cited
- → HKUST-1 MOF in reline deep eutectic solvent: synthesis and phase transformation(2021)44 cited
- → l-(+)-Tartaric acid and choline chloride based deep eutectic solvent: An efficient and reusable medium for synthesis of N-substituted pyrroles via Clauson-Kaas reaction(2014)68 cited
- → Multicomponent reaction in deep eutectic solvent for synthesis of substituted 1-aminoalkyl-2-naphthols(2016)51 cited
- → Hybrid green nonaqueous media: tetraethylene glycol modifies the properties of a (choline chloride + urea) deep eutectic solvent(2016)31 cited