Stool DNA testing for the detection of pancreatic cancer
Cancer2011Vol. 118(10), pp. 2623–2631
Citations Over TimeTop 10% of 2011 papers
John B. Kisiel, Tracy C. Yab, William R. Taylor, Suresh T. Chari, Gloria M. Petersen, Douglas W. Mahoney, David A. Ahlquist
Abstract
This study demonstrates that stool assay of a methylated gene marker can detect PanC. Among candidate methylated markers discriminant in tissue, BMP3 alone performed well in stool. Combining methylated BMP3 and mutant KRAS increased stool detection over either marker alone.
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