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Functional Brain Connectivity Patterns of Headache–Mental Disorder Comorbidity in Patients With Migraine
CNS Neuroscience & Therapeutics2025Vol. 31(12), pp. e70710–e70710
Abstract
This was the first "doubly" multivariate analysis identifying functional brain connectivity patterns underlying headache-mental disorder comorbidity in migraineurs. These findings reveal a neurobiological substrate for migraine-mental disorder comorbidity and highlight the potential of these connectivity patterns as biomarkers for diagnosis and treatment prediction.