Associations of viral ribonucleic acid (RNA) shedding patterns with clinical illness and immune responses in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) infection
Clinical & Translational Immunology2020Vol. 9(7), pp. e1160–e1160
Citations Over TimeTop 14% of 2020 papers
Pei Hua Lee, Woo Chiao Tay, Stephanie Sutjipto, Siew‐Wai Fong, Sean Wei Xiang Ong, Wycliff Enli Wei, Yi‐Hao Chan, Li Min Ling, Barnaby Edward Young, Matthias Paul HS Toh, Laurent Rénia, Lisa F. P. Ng, Yee‐Sin Leo, David Chien Lye, Tau Hong Lee
Abstract
Less active T-cell responses at the initial phase of infection were associated with prolonged viral RNA shedding, suggesting that early immune responses are beneficial to control viral load and prevent viral RNA shedding. Intermittent shedding is common and may explain re-detection of viral RNA in recovered patients.
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