Epicardial and endothelial cell activation concurs with extracellular matrix remodeling in atrial fibrillation
Clinical and Translational Medicine2021Vol. 11(11), pp. e558–e558
Citations Over TimeTop 10% of 2021 papers
Nicoline W.E. van den Berg, Makiri Kawasaki, Benedetta Fabrizi, Fransisca A. Nariswari, Arianne C. Verduijn, Jolien Neefs, Robin Wesselink, Rushd Al‐Shama, Allard C. van der Wal, Onno J. de Boer, Jan Aten, Antoine H.G. Driessen, Aldo Jongejan, Joris R. de Groot
Abstract
Our results suggest that EMT and endothelial cell proliferation work in concert and characterize the (myo)fibroblast recruitment and ECM remodeling of AF. These processes could guide future research toward the discovery of targets for AF therapy.
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