A novel tumour suppressor protein encoded by circMAPK14 inhibits progression and metastasis of colorectal cancer by competitively binding to MKK6
Clinical and Translational Medicine2021Vol. 11(10), pp. e613–e613
Citations Over TimeTop 10% of 2021 papers
Lu Wang, Jiahui Zhou, Chuan Zhang, Ranran Chen, Qingyang Sun, Peng Yang, Chaofan Peng, Yuqian Tan, Chi Jin, Tuo Wang, Jiangzhou Ji, Yueming Sun
Abstract
In summary, we reported for the first time that circMAPK14 functioned as a tumour-suppressor by encoding circMAPK14-175aa, which blocked the progression and metastasis of colorectal cancer.
Related Papers
- → Tumorigenesis and cell evolution(1995)
- DMP1's signal pathway via MAPK-ERK(2013)
- Expression of PTTG and its significance in colorectal cancer(2008)
- 探討與MAPK/ERK訊息傳遞相關之新穎微型RNA在訊息傳遞之調控及對黑色素瘤的作用;Exploration of Novel MAPK/ERK Related Micrornas in Regulation of MAPK/ERK Signaling Pathway and Their Functional Effects in Melanoma(2016)
- → Progress of the relationship between aberrant p53 protein and tumorigenesis(2019)