Circular CPM promotes chemoresistance of gastric cancer via activating PRKAA2‐mediated autophagy
Clinical and Translational Medicine2022Vol. 12(1), pp. e708–e708
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Lang Fang, Jialun Lv, Zhe Xuan, Bowen Li, Zheng Li, Zhongyuan He, Fengyuan Li, Jianghao Xu, Sen Wang, Yiwen Xia, Tianlu Jiang, Lu Zhang, Linjun Wang, Diancai Zhang, Hao Xu, Li Yang, Zekuan Xu, Weizhi Wang
Abstract
Our results reveal that circCPM has a crucial role in regulating GC autophagy and 5-FU resistance by targeting PRKAA2. It may function as a new theory basis for assessing the curative effect of GC and reversing 5-FU chemoresistance.
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