Single‐cell RNA sequencing reveals localized tumour ablation and intratumoural immunostimulant delivery potentiate T cell mediated tumour killing
Clinical and Translational Medicine2022Vol. 12(7), pp. e937–e937
Citations Over TimeTop 13% of 2022 papers
Ashley R. Hoover, Kai‐Li Liu, Christa I. DeVette, Jason R. Krawic, Alexandra D. Medcalf, Connor L. West, Tomas Hode, Samuel S.K. Lam, Alana L. Welm, Xiaohong Sun, William H. Hildebrand, Wei R. Chen
Abstract
Overall, our results reveal that LAIT prompts immunological remodelling of T cells by inducing broad proinflammatory responses and inhibiting suppressive signalling to drive antitumour immunity.
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