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COGNITIVE DEFICITS AND FUNCTIONAL OUTCOMES IN MAJOR DEPRESSIVE DISORDER: DETERMINANTS, SUBSTRATES, AND TREATMENT INTERVENTIONS
Depression and Anxiety2013Vol. 30(6), pp. 515–527
Citations Over TimeTop 1% of 2013 papers
Roger S. McIntyre, S. Danielle, Joanna K. Soczynska, Hanna O. Woldeyohannes, Laura Ashley Gallaugher, Paul Kudlow, Mohammad Alsuwaidan, Anusha Baskaran
Abstract
Cognitive deficits in MDD are a principal mediator of psychosocial impairment, notably workforce performance. The hazards posed by cognitive deficits in MDD underscore the need to identify a consensus-based neurocognitive battery for research and clinical purposes. Interventions (pharmacological, behavioral, neuromodulatory) that engage multiple physiological systems implicated in cognitive deficits hold promise to reduce, reverse, and prevent cognitive deficits.
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