Decrease in somatostatin-positive cell density in the amygdala of females with major depression
Depression and Anxiety2016Vol. 34(1), pp. 68–78
Citations Over TimeTop 17% of 2016 papers
Abstract
In summary, we report an MDD-related reduction in the density of detectable SST-positive neurons across several nuclei in the amygdala, with a reduction in SST mRNA per cell restricted to the basomedial nucleus. In the absence of changes in total cell density, these results suggest the possibility of a change in SST cell phenotype rather than cell death in the amygdala of female MDD subjects.
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