Symptomatic amyloid‐related imaging abnormalities in an APOE ε4/ε4 patient treated with aducanumab
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring2020Vol. 12(1), pp. e12101–e12101
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Lawren VandeVrede, Daniel M. Gibbs, Mary Koestler, Renaud La Joie, Peter A. Ljubenkov, Karine Provost, David N. Soleimani‐Meigooni, Amelia Strom, Elena Tsoy, Gil D. Rabinovici, Adam L. Boxer
Abstract
In an APOE ε4/ε4 patient, ARIA symptoms were accompanied by malignant hypertension and epileptiform activity, and pulsed steroids reversed edema. Studies from larger cohorts may clarify the optimal treatment and pathophysiology of ARIA.
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