Representativeness of samples enrolled in Alzheimer's disease research centers
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring2023Vol. 15(2), pp. e12450–e12450
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Miguel Arce Rentería, Taylor M. Mobley, Nicole D. Evangelista, Luis D. Medina, Kacie Deters, Joshua T. Fox‐Fuller, Lex R. Minto, Justina Avila‐Rieger, Brianne M. Bettcher
Abstract
We examined selection factors included in NACC studies compared to a nationally representative sample.Selection factors included demographic and health factors and self-reported memory concerns.Results suggest that NACC participants are not representative of the U.S. population.Importantly, selection factors differed across racial and ethnic groups.Findings are suggestive of selection bias within NACC studies.
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