Prevalence of cerebral amyloid angiopathy and its correlation with Alzheimer's disease and cognition in an autopsy‐confirmed cohort from China
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring2025Vol. 17(2), pp. e70100–e70100
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Xiang‐Sha Yin, Jianru Sun, Xue Wang, Wei Wu, Zhen Chen, Di Zhang, Yuanyuan Xu, Yongmei Chen, Wenying Qiu, Xiaojing Qian, Jun Ni, Chao Ma
Abstract
First reporting of cerebral amyloid angiopathy (CAA) based on an autopsy-confirmed cohort from China.The prevalence of CAA was high in the elderly Chinese sample.Age and apolipoprotein E (APOE) ε4 allele were related to the prevalence of CAA.CAA and Alzheimer's disease (AD) were frequently co-occurred and significantly associated.Subjects with both CAA and AD exhibited aggravated cognitive impairment.
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