Neuroendocrine carcinomas: Cytological mimics and diagnostic dilemmas
Diagnostic Cytopathology2020Vol. 48(5), pp. 440–445
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Saumya Gupta, Parikshaa Gupta, Manish Rohilla, Nalini Gupta, Radhika Srinivasan, Arvind Rajwanshi, Uma Nahar Saikia, Pranab Dey
Abstract
The accurate diagnosis of NEC depends on clinical correlation, meticulous screening for any obvious neuroendocrine features and cell block morphology. Immunohistochemistry is essential for ruling out of tumours of neuroendocrine origin. A Ki67 index is mandatory for grading of all neuroendocrine tumours.
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