Hepatic ALT isoenzymes are elevated in gluconeogenic conditions including diabetes and suppressed by insulin at the protein level
Diabetes/Metabolism Research and Reviews2015Vol. 31(6), pp. 562–571
Citations Over TimeTop 20% of 2015 papers
Abstract
We have shown the similarity and difference in the regulation of ALT isoforms in gluconeogenic conditions at the protein level, supporting that ALT isoenzymes play an important role in glucose metabolism and may be implicated the development of insulin resistance and diabetes.
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