Radical Cascade Cyclization: Reaction of 1,6‐Enynes with Aryl Radicals by Electron Catalysis
European Journal of Organic Chemistry2016Vol. 2016(29), pp. 4961–4964
Citations Over TimeTop 10% of 2016 papers
Abstract
The radical cascade cyclization of various 1,6‐enynes with aryl radicals by electron catalysis under metal‐free reaction conditions was explored. Readily available anilines were used as radical precursors, and the reactions proceeded in the absence of any transition metal. These cascades comprise three C–C bond formations, which provide polycyclic structures with extended π‐systems. The photophysical properties of some of these novel compounds were investigated, and a plausible reaction mechanism is proposed.
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