Adjuvant therapy with flutamide for presurgical volume reduction in juvenile nasopharyngeal angiofibroma
Head & Neck2011Vol. 33(12), pp. 1747–1753
Citations Over TimeTop 10% of 2011 papers
Alok Thakar, Gaurav Gupta, Ashu Seith Bhalla, Vandana Jain, Suresh C. Sharma, Raju Sharma, Sudhir Bahadur, Ramesh Chandra Deka
Abstract
Prepubertal and postpubertal patients differ in their response to flutamide. In postpubertal patients, 6 weeks preoperative use is safe and leads to partial tumor regression. Tumor regression from adjacent vital structures may facilitate surgical excision and limit morbidity.
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