Staging and treatment of oropharyngeal cancer in the human papillomavirus era
Head & Neck2014Vol. 37(7), pp. 1002–1013
Citations Over TimeTop 10% of 2014 papers
Matthew J. Ward, Toby Mellows, Scott Harris, Andrew Webb, Nimesh Patel, Hugh J. Cox, Kim Piper, Christian H. Ottensmeier, Gareth J. Thomas, Emma V. King
Abstract
These data suggest that the current TNM system has little prognostic value in HPV-positive oropharyngeal SCC. Patients with HPV-positive tumors show improved survival independent of treatment. The addition of chemotherapy increases the risk of feeding tube dependency and could potentially be avoided in T1/T2 HPV-positive tumors without compromising survival.