Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke
Head & Neck2014Vol. 37(11), pp. 1642–1649
Citations Over TimeTop 10% of 2014 papers
Ryan Li, Daniel L. Faden, Carole Fakhry, Chaz Langelier, Yuchen Jiao, Yuxuan Wang, Matthew D. Wilkerson, Chandra Sekhar Pedamallu, Matthew Old, James C. Lang, Myriam Loyo, Sun Mi Ahn, Marietta Tan, Zhen Gooi, Jason Y. K. Chan, Jeremy D. Richmon, Laura D. Wood, Ralph H. Hruban, Justin A. Bishop, William H. Westra, Christine H. Chung, Joseph A. Califano, Christine G. Gourin, Chetan Bettegowda, Matthew Meyerson, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein, Joseph L. DeRisi, Wayne M. Koch, Nishant Agrawal
Abstract
The young age of nonsmoking patients with oral tongue cancer and fewer TP53 mutations suggest a viral role in this disease. Our efforts to identify such a virus were unsuccessful. Further studies are warranted to elucidate the drivers of carcinogenesis in these patients.
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