Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasis
Hepatology2008Vol. 47(5), pp. 1578–1586
Citations Over TimeTop 11% of 2008 papers
Young Joo Park, Mohammed Qatanani, Steven S. Chua, Jennifer L. LaRey, Stacy A. Johnson, Mitsuhiro Watanabe, David D. Moore, Yoon Kwang Lee
Abstract
We propose that differences in acute responses to BDL, particularly the early formation of bile infarcts, are a primary determinant of the differences in longer term sensitivity of the Fxr(-/-) and Shp(-/-) mice to acute obstructive cholestasis.
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