Background progenitor activation is associated with recurrence after hepatectomy of combined hepatocellular-cholangiocarcinoma
Hepatology2012Vol. 56(5), pp. 1804–1816
Citations Over TimeTop 10% of 2012 papers
Xiong Cai, Jian Zhai, David E. Kaplan, Yijun Zhang, Zhou Lining, Xutao Chen, Guangyang Qian, Qiudong Zhao, Yonghai Li, Lu Gao, Wen‐Ming Cong, Ming-hua Zhu, Zhenlin Yan, Lehua Shi, Dong Wu, Lixin Wei, Feng Shen, Mengchao Wu
Abstract
Proliferative ductular reaction related to HPC activation is associated with recurrence of CHC. Background HPC activation is strongly associated with multifocal occurrence and related tumor recurrence, highlighting the critical role of background liver disease, a "field effect," in the recurrence of CHC.
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