Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma
Hepatology2020Vol. 73(3), pp. 1028–1044
Citations Over TimeTop 10% of 2020 papers
Zoe Hall, Davide Chiarugi, Evelina Charidemou, Jack Leslie, Emma Scott, Luca Pellegrinet, Michael Allison, Gabriele Mocciaro, Quentin M. Anstee, Gérard I. Evan, Matthew Hoare, Antonio Vidal‐Puig, Fiona Oakley, Michèle Vacca, Julian L. Griffin
Abstract
Overall, we demonstrate that specific lipid metabolic pathways are coherently altered when hepatocytes switch to proliferation. These represent a source of targets for the development of therapeutic strategies and prognostic biomarkers of HCC.
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