Clinical study ofl‐asparaginase in the treatment of extranodal NK/T‐cell lymphoma, nasal type
Citations Over TimeTop 13% of 2015 papers
Abstract
Extranodal natural killer/T-cell lymphoma, nasal type, (ENKTL) is a rare distinct entity of non-Hodgkin lymphoma. It is prevalent in Asia and Latin America but rare in North America and Europe. ENKTL represents an aggressive clinical course and a poor prognosis especially for advanced disease. There is no standard chemotherapeutic regimen for ENKTL. Recently, the efficacy of l-asparaginase in ENKTL has been confirmed. A series of l-asparaginase-containing chemotherapeutic regimens have been studied in clinical trials and have significantly improved the efficacy and prognosis for patients with ENKTL. This review will focus on pharmacology of l-asparaginase, the efficacy of a series of l-asparaginase-containing regimens in the treatment of ENKTL and future clinical study directions of l-asparaginase-containing regimens in ENKTL. Copyright © 2015 John Wiley & Sons, Ltd.
Related Papers
- → Chromosomal abnormalities of 200 Chinese patients with non-Hodgkin's lymphoma in Taiwan: with special reference to T-cell lymphoma(2004)38 cited
- → Diffuse T-Cell Lymphoma Preceded by Nodular Lymphoma(1982)19 cited
- Detection of Epstein-Barr virus in Tcell lymphoma and clinicopathologic analysis(2003)
- [Detection of Epstein-Barr virus in T cell lymphoma and clinicopathologic analysis].(2003)
- Detection of the 30 base pair deletion of Epstein-Barr virus latent membrane protein 1 in extranodal nasal type NK/T-cell lymphoma and its prognostic significance(2005)