Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(−/−) mice
Inflammatory Bowel Diseases2008Vol. 14(5), pp. 620–631
Citations Over TimeTop 12% of 2008 papers
Andrew Collett, Norman B. Higgs, Meritxell Gironella, Leo Zeef, Andrew Hayes, Emil Salmo, Najib Haboubi, Juan Iovanna, Gordon Carlson, Geoffrey Warhurst
Abstract
These studies show that early epithelial changes associated with altered responsiveness to bacteria precede increased permeability and mucosal inflammation in this model of colitis, highlighting the importance of P-glycoprotein in regulating interactions with the commensal microflora.
Related Papers
- → Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains(1997)402 cited
- → Localization of Idd11 using NOD congenic mouse strains: elimination of Slc9a1 as a candidate gene(2000)35 cited
- → Congenic Rats For Hypertension: How Useful Are They For The Hunting Of Hypertension Genes?(2000)32 cited
- → Epistatic effects of multiple congenic regions on blood pressure and heart weight in Dahl rats under salt‐loading conditions(2012)