Contribution of TNFSF15 gene variants to Crohnʼs disease susceptibility confirmed in UK population
Inflammatory Bowel Diseases2008Vol. 14(6), pp. 733–737
Citations Over TimeTop 10% of 2008 papers
Mark Tremelling, Carlo Berzuini, Dunecan Massey, Francesca Bredin, C.J. Price, Claire Dawson, Sheila Bingham, Miles Parkes
Abstract
Variants in TNFSF15 contribute to overall CD susceptibility in European populations, although to a lesser extent than that seen in the Japanese. Further studies to define the precise disease-causing variants as well as targeted functional studies are now required in human CD as TNFSF15 is a potential target for biological therapies.
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