Granulocyte-macrophage colony-stimulating factor elicits bone marrow-derived cells that promote efficient colonic mucosal healing
Inflammatory Bowel Diseases2009Vol. 16(3), pp. 428–441
Citations Over TimeTop 10% of 2009 papers
Eric Bernasconi, Laurent Favre, Michel H. Maillard, Daniel Bachmann, Catherine Pythoud, Hanifa Bouzourène, Ed Croze, Sharlene Velichko, John F. Parkinson, Pierre Michetti, Dominique Velin
Abstract
Our study shows that GM-CSF-dependent stimulation of bone marrow-derived cells during DSS-induced colitis accelerates colonic tissue repair. These data provide a putative mechanism for the observed beneficial effects of GM-CSF therapy in Crohn's disease.
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