Genome wide association (GWA) predictors of anti-TNFα therapeutic responsiveness in pediatric inflammatory bowel disease
Inflammatory Bowel Diseases2009Vol. 16(8), pp. 1357–1366
Citations Over TimeTop 10% of 2009 papers
Marla C. Dubinsky, Ling Mei, Madison Friedman, Tanvi Dhere, Talin Haritunians, Håkon Håkonarson, Cecilia Kim, Joseph Glessner, Stephan R. Targan, Dermot McGovern, Kent D. Taylor, Jerome I. Rotter
Abstract
The combination of phenotype and genotype is most predictive of primary nonresponse to anti-TNFalpha in pediatric IBD. Defining predictors of response to anti-TNFalpha may allow the identification of patients who will not benefit from this class of therapy.
Related Papers
- → Gene and pathway-based second-wave analysis of genome-wide association studies(2009)240 cited
- → Technical Reproducibility of Genotyping SNP Arrays Used in Genome-Wide Association Studies(2012)72 cited
- → Lessons and implications from association studies and post-GWAS analyses of cervical cancer(2014)59 cited
- → Genome-wide association studies in aging-related processes such as diabetes mellitus, atherosclerosis and cancer(2007)43 cited
- → GWAS summary-based pathway analysis correcting for the genetic confounding impact of environmental exposures(2017)4 cited