Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma
Immunity Inflammation and Disease2020Vol. 8(1), pp. 40–49
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Abstract
There was increased expression of DNASE1L3 in asthma and IL1B in neutrophilic asthma. These results show similar upregulated patterns of expression in two genes of the 6GS in endobronchial biopsies, previously identified in sputum. The upregulation of DNASE1L3 and IL1B suggests that common mechanisms may be at play throughout the airway.
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