Interaction between 12p chromosomal abnormalities and Lnc‐HOTAIR mediated pathway in acute myeloid leukemia
Journal of Cellular Biochemistry2019Vol. 120(9), pp. 15288–15296
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Nashwa El‐Khazragy, Sherief Ghozy, Safa Matbouly, Walid Zaki, Gehan Safwat, Ghada Hussien, Omar Khalifa
Abstract
12p abnormalities associated AML were associated with worse prognosis. Our results proved that HOTAIR, miR-193a, and c-kit genes are independent prognostic predictors in 12p chromosomal associated AML; therefore it may represent a novel therapeutic application in AML in the future.
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