Upregulation of expression from the FRDA genomic locus for the therapy of Friedreich ataxia
The Journal of Gene Medicine2002Vol. 5(1), pp. 72–81
Citations Over TimeTop 18% of 2002 papers
Abstract
Expression studies with FRDA-EGFP fusion constructs will facilitate delineation of regulatory elements determining the tissue and developmental specificity of FRDA gene expression. These constructs should also facilitate screening for pharmacological compounds that can modulate the expression of the FRDA gene in a clinically relevant manner.
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