Insights into the mechanism of magnetofection using PEI‐based magnetofectins for gene transfer
The Journal of Gene Medicine2004Vol. 6(8), pp. 923–936
Citations Over TimeTop 10% of 2004 papers
Stephanie Huth, James Lausier, Søren W. Gersting, Carsten Rudolph, Christian Plank, Ulrich Welsch, Joseph Rosenecker
Abstract
The magnetic field itself does not alter the uptake mechanism of magnetofectins. Obviously, the magnetic forces lead to an accelerated sedimentation of magnetofectins on the cell surface and do not directly affect the endocytic uptake mechanism. So further improvement of magnetic field application could lead to efficient targeting of gene expression into the desired organ and tissue in vivo.
Related Papers
- → Macropinocytosis: an endocytic pathway for internalising large gulps(2011)684 cited
- → Defining Macropinocytosis(2009)675 cited
- → The effect of the size of fluorescent dextran on its endocytic pathway(2015)205 cited
- → Micro-/nano-electroporation for active gene delivery(2015)44 cited
- → Endocytic and Exocytic Transport Assays(2001)