Phenomenology of “Lubag” or X‐linked dystonia–parkinsonism
Movement Disorders2002Vol. 17(6), pp. 1271–1277
Citations Over Time
Virgilio Gerald H. Evidente, Joel Advincula, Raymund P. Esteban, Paul Matthew D. Pasco, Jhoe Anthony R. Alfon, Filipinas F. Natividad, Joven R. Cuanang, Amado San Luis, Katrina Gwinn, John Hardy, Dena Hernandez, Andrew Singleton
Abstract
X-linked dystonia-parkinsonism (XDP), or Lubag syndrome, is known to cause progressive dystonia, with or without parkinsonism, among Filipino male adults with maternal roots from the Philippine island of Panay. We present cinematographic material of 11 cases of Lubag carrying the XDP haplotypes who manifest with a wide spectrum of movement disorders, including dystonia, tremor, parkinsonism, myoclonus, chorea, and myorhythmia. Because of overlapping features, Lubag patients are commonly misdiagnosed as idiopathic dystonia, essential tremor, Parkinson's disease, or Parkinson's-plus syndromes. Thus, it is imperative to elicit an exhaustive family history in any Filipino male adult who presents with a movement disorder.
Related Papers
- → Non-choreic movement disorders as initial manifestations of Huntington's disease(2007)21 cited
- [Choreic dyskinesia and GABA - pharmaco-clinical approach. Preliminary note].(1978)
- → TREATMENT OF MOVEMENT DISORDERS IN BENIGN FAMILIAL CHOREA(1992)
- → A Case Report of Late Onset Chorea Hyperglycemia Basal Ganglia Syndrome using <i>Yokukan-san</i>(2020)
- → Movement Disorders II: Chorea, Dystonia, Myoclonus, and Tremor(2010)