A critique of the second consensus criteria for multiple system atrophy
Movement Disorders2019Vol. 34(7), pp. 975–984
Citations Over TimeTop 10% of 2019 papers
Iva Stanković, Niall Quinn, Luca Vignatelli, Angelo Antonini, Daniela Berg, Elizabeth A. Coon, Pietro Cortelli, Alessandra Fanciulli, Joaquim J. Ferreira, Roy Freeman, Glenda M. Halliday, Günter U. Höglinger, Valeria Iodice, Horacio Kaufmann, Thomas Klockgether, Vladimir Kostić, Florian Krismer, Anthony E. Lang, Johannes Levin, Phillip A. Low, Christopher J. Mathias, Wassilios G. Meissner, Lucy Norcliffe Kaufmann, Jose‐Alberto Palma, Jalesh N. Panicker, Maria Teresa Pellecchia, Ryuji Sakakibara, Jeremy D. Schmahmann, Sonja W. Scholz, Wolfgang Singer, María Stamelou, Eduardo Tolosa, Shoji Tsuji, Klaus Seppi, Werner Poewe, Gregor K. Wenning, on behalf of the Movement Disorder Society Multiple System Atrophy Study Group
Abstract
Multiple system atrophy (MSA) is an adult-onset progressive neurodegenerative disorder that manifests clinically with autonomic failure, parkinsonism, and ataxia in any combination. Oligodendroglial cytoplasmatic inclusions consisting of misfoldedα-synuclein are a pathological hallmark of disease. The clinical diagnosisof MSA is typically delayed as a result of incomplete or nonspecific manifestations during early disease stages.
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